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CRISPR/Cas9-based genome editing for simultaneous interference with gene expression and protein stability

Interference with genes is the foundation of reverse genetics and is key to manipulation of living cells for biomedical and biotechnological applications. However, classical genetic knockout and transcriptional knockdown technologies have different drawbacks and offer no control over existing protei...

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Detalles Bibliográficos
Autores principales:	Martínez, Virginia, Lauritsen, Ida, Hobel, Tonja, Li, Songyuan, Nielsen, Alex Toftgaard, Nørholm, Morten H. H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2017
Materias:	Methods Online
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5714205/ https://www.ncbi.nlm.nih.gov/pubmed/28981713 http://dx.doi.org/10.1093/nar/gkx797

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