2′-Fluoroarabinonucleic acid modification traps G-quadruplex and i-motif structures in human telomeric DNA

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Human telomeres and promoter regions of genes fulfill a significant role in cellular aging and cancer. These regions comprise of guanine and cytosine-rich repeats, which under certain conditions can fold into G-quadruplex (G4) and i-motif structures, respectively. Herein, we use UV, circular dichroi...

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Detalles Bibliográficos
Autores principales: Abou Assi, Hala, El-Khoury, Roberto, González, Carlos, Damha, Masad J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Chemical Biology and Nucleic Acid Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5714228/
https://www.ncbi.nlm.nih.gov/pubmed/29036537
http://dx.doi.org/10.1093/nar/gkx838

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5714228/
https://www.ncbi.nlm.nih.gov/pubmed/29036537
http://dx.doi.org/10.1093/nar/gkx838

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