Quantitating translational control: mRNA abundance-dependent and independent contributions and the mRNA sequences that specify them

Translation rate per mRNA molecule correlates positively with mRNA abundance. As a result, protein levels do not scale linearly with mRNA levels, but instead scale with the abundance of mRNA raised to the power of an ‘amplification exponent’. Here we show that to quantitate translational control, th...

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Detalles Bibliográficos
Autores principales: Li, Jingyi Jessica, Chew, Guo-Liang, Biggin, Mark D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Genomics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5714229/
https://www.ncbi.nlm.nih.gov/pubmed/29040683
http://dx.doi.org/10.1093/nar/gkx898

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5714229/
https://www.ncbi.nlm.nih.gov/pubmed/29040683
http://dx.doi.org/10.1093/nar/gkx898

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