The nuclear mitotic apparatus protein NuMA controls rDNA transcription and mediates the nucleolar stress response in a p53-independent manner

The nuclear mitotic apparatus protein, NuMA, is involved in major cellular events such as DNA damage response, apoptosis and p53-mediated growth-arrest, all of which are under the control of the nucleolus upon stress. Proteomic investigation has identified NuMA among hundreds of nucleolar proteins....

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Detalles Bibliográficos
Autores principales: Jayaraman, Swaathi, Chittiboyina, Shirisha, Bai, Yunfeng, Abad, Patricia C., Vidi, Pierre-Alexandre, Stauffacher, Cynthia V., Lelièvre, Sophie A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5714241/
https://www.ncbi.nlm.nih.gov/pubmed/28981686
http://dx.doi.org/10.1093/nar/gkx782

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