Mycobacterium avium subspecies hominissuis in Crohn’s disease: a case report

We have cultured Mycobacteria avium subspecies hominissuis (MAH) from the blood of a patient with Crohn’s disease. The patient is a 21 year-old-female with a diagnosis of Crohn’s disease for two years. She had been treated with corticosteroids and Humira for six months. A blood specimen was cultured...

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Autores principales: Zhang, Peilin, Minardi, Lawrence M, Kuenstner, J Todd, Kruzelock, Rusty
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Case Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5714243/
https://www.ncbi.nlm.nih.gov/pubmed/26510454
http://dx.doi.org/10.1093/gastro/gov054
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author Zhang, Peilin
Minardi, Lawrence M
Kuenstner, J Todd
Kruzelock, Rusty
author_facet Zhang, Peilin
Minardi, Lawrence M
Kuenstner, J Todd
Kruzelock, Rusty
author_sort Zhang, Peilin
collection PubMed
description We have cultured Mycobacteria avium subspecies hominissuis (MAH) from the blood of a patient with Crohn’s disease. The patient is a 21 year-old-female with a diagnosis of Crohn’s disease for two years. She had been treated with corticosteroids and Humira for six months. A blood specimen was cultured in a specialized medium, and there was visible bacterial growth present in the liquid culture medium after eight weeks. PCR analysis of the bacterial growth and subsequent direct sequencing of the PCR amplicon confirmed the presence of MAH. The significance of this finding is discussed.
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spelling pubmed-57142432017-12-08 Mycobacterium avium subspecies hominissuis in Crohn’s disease: a case report Zhang, Peilin Minardi, Lawrence M Kuenstner, J Todd Kruzelock, Rusty Gastroenterol Rep (Oxf) Case Reports We have cultured Mycobacteria avium subspecies hominissuis (MAH) from the blood of a patient with Crohn’s disease. The patient is a 21 year-old-female with a diagnosis of Crohn’s disease for two years. She had been treated with corticosteroids and Humira for six months. A blood specimen was cultured in a specialized medium, and there was visible bacterial growth present in the liquid culture medium after eight weeks. PCR analysis of the bacterial growth and subsequent direct sequencing of the PCR amplicon confirmed the presence of MAH. The significance of this finding is discussed. Oxford University Press 2017-11 2015-10-27 /pmc/articles/PMC5714243/ /pubmed/26510454 http://dx.doi.org/10.1093/gastro/gov054 Text en © The Author(s) 2015. Published by Oxford University Press and the Digestive Science Publishing Co. Limited. http://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Reports
Zhang, Peilin
Minardi, Lawrence M
Kuenstner, J Todd
Kruzelock, Rusty
Mycobacterium avium subspecies hominissuis in Crohn’s disease: a case report
title Mycobacterium avium subspecies hominissuis in Crohn’s disease: a case report
title_full Mycobacterium avium subspecies hominissuis in Crohn’s disease: a case report
title_fullStr Mycobacterium avium subspecies hominissuis in Crohn’s disease: a case report
title_full_unstemmed Mycobacterium avium subspecies hominissuis in Crohn’s disease: a case report
title_short Mycobacterium avium subspecies hominissuis in Crohn’s disease: a case report
title_sort mycobacterium avium subspecies hominissuis in crohn’s disease: a case report
topic Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5714243/
https://www.ncbi.nlm.nih.gov/pubmed/26510454
http://dx.doi.org/10.1093/gastro/gov054
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AT kruzelockrusty mycobacteriumaviumsubspecieshominissuisincrohnsdiseaseacasereport

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