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Structural basis for the substrate selectivity of Helicobacter pylori NucT nuclease activity
The Phospholipase D (PLD) superfamily of proteins includes a group of enzymes with nuclease activity on various nucleic acid substrates. Here, with the aim of better understanding the substrate specificity determinants in this subfamily, we have characterised the enzymatic activity and the crystal s...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5714352/ https://www.ncbi.nlm.nih.gov/pubmed/29206236 http://dx.doi.org/10.1371/journal.pone.0189049 |