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Structural basis for the substrate selectivity of Helicobacter pylori NucT nuclease activity

The Phospholipase D (PLD) superfamily of proteins includes a group of enzymes with nuclease activity on various nucleic acid substrates. Here, with the aim of better understanding the substrate specificity determinants in this subfamily, we have characterised the enzymatic activity and the crystal s...

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Detalles Bibliográficos
Autores principales: Celma, Louisa, Corbinais, Christopher, Vercruyssen, Julien, Veaute, Xavier, de la Sierra-Gallay, Inès Li, Guérois, Raphaël, Busso, Didier, Mathieu, Aurélie, Marsin, Stéphanie, Quevillon-Cheruel, Sophie, Radicella, J. Pablo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5714352/
https://www.ncbi.nlm.nih.gov/pubmed/29206236
http://dx.doi.org/10.1371/journal.pone.0189049