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Development and preliminary evaluation of a multiplexed amplification and next generation sequencing method for viral hemorrhagic fever diagnostics

BACKGROUND: We describe the development and evaluation of a novel method for targeted amplification and Next Generation Sequencing (NGS)-based identification of viral hemorrhagic fever (VHF) agents and assess the feasibility of this approach in diagnostics. METHODOLOGY: An ultrahigh-multiplex panel...

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Detalles Bibliográficos
Autores principales:	Brinkmann, Annika, Ergünay, Koray, Radonić, Aleksandar, Kocak Tufan, Zeliha, Domingo, Cristina, Nitsche, Andreas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5714388/ https://www.ncbi.nlm.nih.gov/pubmed/29155823 http://dx.doi.org/10.1371/journal.pntd.0006075

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