Glutamate is required for depression but not potentiation of long-term presynaptic function

Hebbian plasticity is thought to require glutamate signalling. We show this is not the case for hippocampal presynaptic long-term potentiation (LTP(pre)), which is expressed as an increase in transmitter release probability (P(r)). We find that LTP(pre) can be induced by pairing pre- and postsynapti...

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Detalles Bibliográficos
Autores principales: Padamsey, Zahid, Tong, Rudi, Emptage, Nigel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5714480/
https://www.ncbi.nlm.nih.gov/pubmed/29140248
http://dx.doi.org/10.7554/eLife.29688