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SID-1 Domains Important for dsRNA Import in Caenorhabditis elegans

In the nematode Caenorhabditis elegans, RNA interference (RNAi) triggered by double-stranded RNA (dsRNA) spreads systemically to cause gene silencing throughout the organism and its progeny. We confirm that Caenorhabditis nematode SID-1 orthologs have dsRNA transport activity and demonstrate that th...

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Detalles Bibliográficos
Autores principales: Whangbo, Jennifer S., Weisman, Alexandra S., Chae, Jeiwook, Hunter, Craig P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5714486/
https://www.ncbi.nlm.nih.gov/pubmed/29025917
http://dx.doi.org/10.1534/g3.117.300308