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Modulation of Global Transcriptional Regulatory Networks as a Strategy for Increasing Kanamycin Resistance of the Translational Elongation Factor-G Mutants in Escherichia coli

Evolve and resequence experiments have provided us a tool to understand bacterial adaptation to antibiotics. In our previous work, we used short-term evolution to isolate mutants resistant to the ribosome targeting antibiotic kanamycin, and reported that Escherichia coli develops low cost resistance...

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Detalles Bibliográficos
Autores principales:	Mogre, Aalap, Veetil, Reshma T., Seshasayee, Aswin Sai Narain
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Genetics Society of America 2017
Materias:	Investigations
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5714492/ https://www.ncbi.nlm.nih.gov/pubmed/29046437 http://dx.doi.org/10.1534/g3.117.300284

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