Regulatory T Cell Migration Is Dependent on Glucokinase-Mediated Glycolysis

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Migration of activated regulatory T (Treg) cells to inflamed tissue is crucial for their immune-modulatory function. While metabolic reprogramming during Treg cell differentiation has been extensively studied, the bioenergetics of Treg cell trafficking remains undefined. We have investigated the met...

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Detalles Bibliográficos
Autores principales: Kishore, Madhav, Cheung, Kenneth C.P., Fu, Hongmei, Bonacina, Fabrizia, Wang, Guosu, Coe, David, Ward, Eleanor J., Colamatteo, Alessandra, Jangani, Maryam, Baragetti, Andrea, Matarese, Giuseppe, Smith, David M., Haas, Robert, Mauro, Claudio, Wraith, David C., Okkenhaug, Klaus, Catapano, Alberico L., De Rosa, Veronica, Norata, Giuseppe D., Marelli-Berg, Federica M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5714502/
https://www.ncbi.nlm.nih.gov/pubmed/29166588
http://dx.doi.org/10.1016/j.immuni.2017.10.017
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