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Lung SBRT: dosimetric and delivery comparison of RapidArc, TomoTherapy, and IMRT

This study seeks to compare fixed‐field intensity‐modulated radiation therapy (FF IMRT), RapidArc (RA), and helical tomotherapy (HT) to discover the optimal treatment modality to deliver SBRT to the peripheral lung. Eight patients with peripheral primary lung cancer were reviewed. Plans were prescri...

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Autores principales: Weyh, Ashleigh, Konski, Andre, Nalichowski, Adrian, Maier, Jordan, Lack, Danielle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5714522/
https://www.ncbi.nlm.nih.gov/pubmed/23835374
http://dx.doi.org/10.1120/jacmp.v14i4.4065
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author Weyh, Ashleigh
Konski, Andre
Nalichowski, Adrian
Maier, Jordan
Lack, Danielle
author_facet Weyh, Ashleigh
Konski, Andre
Nalichowski, Adrian
Maier, Jordan
Lack, Danielle
author_sort Weyh, Ashleigh
collection PubMed
description This study seeks to compare fixed‐field intensity‐modulated radiation therapy (FF IMRT), RapidArc (RA), and helical tomotherapy (HT) to discover the optimal treatment modality to deliver SBRT to the peripheral lung. Eight patients with peripheral primary lung cancer were reviewed. Plans were prescribed a dose of 48 Gy and optimized similarly with heterogeneity corrections. Plan quality was assessed using conformality index ([Formula: see text]), homogeneity index (HI), the ratio of the 50% isodose volume to PTV ([Formula: see text]) to assess intermediate dose spillage, and normal tissue constraints. Delivery efficiency was evaluated using treatment time and MUs. Dosimetric accuracy was assessed using gamma index (3% dose difference, 3 mm DTA, 10% threshold), and measured with a PTW ARRAY seven29 and OCTAVIUS phantom. [Formula: see text] , and [Formula: see text] were lowest for HT compared to seven‐field coplanar IMRT and two‐arc coplanar RA ([Formula: see text]). Normal tissue constraints were met for all modalities, except maximum rib dose due to close proximity to the PTV. RA reduced delivery time by 60% compared to HT, and 40% when compared to FF IMRT. RA also reduced the mean MUs by 77% when compared to HT, and by 22% compared to FF IMRT. All modalities can be delivered accurately, with mean QA pass rates over 97%. For peripheral lung SBRT treatments, HT performed better dosimetrically, reducing maximum rib dose, as well as improving dose conformity and uniformity. RA and FF IMRT plan quality was equivalent to HT for patients with minimal or no overlap of the PTV with the chest wall, but was reduced for patients with a larger overlap. RA and IMRT were equivalent, but the reduced treatment times of RA make it a more efficient modality. PACS numbers: 87.53.Ly87.55.N‐, 87.55.D‐, 87.56.bd
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spelling pubmed-57145222018-04-02 Lung SBRT: dosimetric and delivery comparison of RapidArc, TomoTherapy, and IMRT Weyh, Ashleigh Konski, Andre Nalichowski, Adrian Maier, Jordan Lack, Danielle J Appl Clin Med Phys Radiation Oncology Physics This study seeks to compare fixed‐field intensity‐modulated radiation therapy (FF IMRT), RapidArc (RA), and helical tomotherapy (HT) to discover the optimal treatment modality to deliver SBRT to the peripheral lung. Eight patients with peripheral primary lung cancer were reviewed. Plans were prescribed a dose of 48 Gy and optimized similarly with heterogeneity corrections. Plan quality was assessed using conformality index ([Formula: see text]), homogeneity index (HI), the ratio of the 50% isodose volume to PTV ([Formula: see text]) to assess intermediate dose spillage, and normal tissue constraints. Delivery efficiency was evaluated using treatment time and MUs. Dosimetric accuracy was assessed using gamma index (3% dose difference, 3 mm DTA, 10% threshold), and measured with a PTW ARRAY seven29 and OCTAVIUS phantom. [Formula: see text] , and [Formula: see text] were lowest for HT compared to seven‐field coplanar IMRT and two‐arc coplanar RA ([Formula: see text]). Normal tissue constraints were met for all modalities, except maximum rib dose due to close proximity to the PTV. RA reduced delivery time by 60% compared to HT, and 40% when compared to FF IMRT. RA also reduced the mean MUs by 77% when compared to HT, and by 22% compared to FF IMRT. All modalities can be delivered accurately, with mean QA pass rates over 97%. For peripheral lung SBRT treatments, HT performed better dosimetrically, reducing maximum rib dose, as well as improving dose conformity and uniformity. RA and FF IMRT plan quality was equivalent to HT for patients with minimal or no overlap of the PTV with the chest wall, but was reduced for patients with a larger overlap. RA and IMRT were equivalent, but the reduced treatment times of RA make it a more efficient modality. PACS numbers: 87.53.Ly87.55.N‐, 87.55.D‐, 87.56.bd John Wiley and Sons Inc. 2013-07-08 /pmc/articles/PMC5714522/ /pubmed/23835374 http://dx.doi.org/10.1120/jacmp.v14i4.4065 Text en © 2013 The Authors. This is an open access article under the terms of the http://creativecommons.org/licenses/by/3.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Radiation Oncology Physics
Weyh, Ashleigh
Konski, Andre
Nalichowski, Adrian
Maier, Jordan
Lack, Danielle
Lung SBRT: dosimetric and delivery comparison of RapidArc, TomoTherapy, and IMRT
title Lung SBRT: dosimetric and delivery comparison of RapidArc, TomoTherapy, and IMRT
title_full Lung SBRT: dosimetric and delivery comparison of RapidArc, TomoTherapy, and IMRT
title_fullStr Lung SBRT: dosimetric and delivery comparison of RapidArc, TomoTherapy, and IMRT
title_full_unstemmed Lung SBRT: dosimetric and delivery comparison of RapidArc, TomoTherapy, and IMRT
title_short Lung SBRT: dosimetric and delivery comparison of RapidArc, TomoTherapy, and IMRT
title_sort lung sbrt: dosimetric and delivery comparison of rapidarc, tomotherapy, and imrt
topic Radiation Oncology Physics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5714522/
https://www.ncbi.nlm.nih.gov/pubmed/23835374
http://dx.doi.org/10.1120/jacmp.v14i4.4065
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