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Dosimetric characterization and optimization of a customized Stanford Total Skin Electron Irradiation (TSEI) technique

Total skin electron irradiation (TSEI) has been used as a treatment for mycosis fungoides. Our center has implemented a modified Stanford technique with six pairs of 6 MeV adjacent electron beams, incident perpendicularly on the patient who remains lying on a translational platform, at 200 cm from t...

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Autores principales: Lučić, Felipe, Sánchez‐Nieto, Beatriz, Caprile, Paola, Zelada, Gabriel, Goset, Karen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5714578/
https://www.ncbi.nlm.nih.gov/pubmed/24036877
http://dx.doi.org/10.1120/jacmp.v14i5.4388
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author Lučić, Felipe
Sánchez‐Nieto, Beatriz
Caprile, Paola
Zelada, Gabriel
Goset, Karen
author_facet Lučić, Felipe
Sánchez‐Nieto, Beatriz
Caprile, Paola
Zelada, Gabriel
Goset, Karen
author_sort Lučić, Felipe
collection PubMed
description Total skin electron irradiation (TSEI) has been used as a treatment for mycosis fungoides. Our center has implemented a modified Stanford technique with six pairs of 6 MeV adjacent electron beams, incident perpendicularly on the patient who remains lying on a translational platform, at 200 cm from the source. The purpose of this study is to perform a dosimetric characterization of this technique and to investigate its optimization in terms of energy characteristics, extension, and uniformity of the treatment field. In order to improve the homogeneity of the distribution, a custom‐made polyester filter of variable thickness and a uniform PMMA degrader plate were used. It was found that the characteristics of a 9 MeV beam with an 8 mm thick degrader were similar to those of the 6 MeV beam without filter, but with an increased surface dose. The combination of the degrader and the polyester filter improved the uniformity of the distribution along the dual field (180 cm long), increasing the dose at the borders of field by 43%. The optimum angles for the pair of beams were [Formula: see text]. This configuration avoided displacement of the patient, and reduced the treatment time and the positioning problems related to the abutting superior and inferior fields. Dose distributions in the transversal plane were measured for the six incidences of the Stanford technique with film dosimetry in an anthropomorphic pelvic phantom. This was performed for the optimized treatment and compared with the previously implemented technique. The comparison showed an increased superficial dose and improved uniformity of the 85% isodose curve coverage for the optimized technique. PACS numbers: 87.53.Bn, 87.55.ne, 87.56.bd
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spelling pubmed-57145782018-04-02 Dosimetric characterization and optimization of a customized Stanford Total Skin Electron Irradiation (TSEI) technique Lučić, Felipe Sánchez‐Nieto, Beatriz Caprile, Paola Zelada, Gabriel Goset, Karen J Appl Clin Med Phys Radiation Oncology Physics Total skin electron irradiation (TSEI) has been used as a treatment for mycosis fungoides. Our center has implemented a modified Stanford technique with six pairs of 6 MeV adjacent electron beams, incident perpendicularly on the patient who remains lying on a translational platform, at 200 cm from the source. The purpose of this study is to perform a dosimetric characterization of this technique and to investigate its optimization in terms of energy characteristics, extension, and uniformity of the treatment field. In order to improve the homogeneity of the distribution, a custom‐made polyester filter of variable thickness and a uniform PMMA degrader plate were used. It was found that the characteristics of a 9 MeV beam with an 8 mm thick degrader were similar to those of the 6 MeV beam without filter, but with an increased surface dose. The combination of the degrader and the polyester filter improved the uniformity of the distribution along the dual field (180 cm long), increasing the dose at the borders of field by 43%. The optimum angles for the pair of beams were [Formula: see text]. This configuration avoided displacement of the patient, and reduced the treatment time and the positioning problems related to the abutting superior and inferior fields. Dose distributions in the transversal plane were measured for the six incidences of the Stanford technique with film dosimetry in an anthropomorphic pelvic phantom. This was performed for the optimized treatment and compared with the previously implemented technique. The comparison showed an increased superficial dose and improved uniformity of the 85% isodose curve coverage for the optimized technique. PACS numbers: 87.53.Bn, 87.55.ne, 87.56.bd John Wiley and Sons Inc. 2013-09-06 /pmc/articles/PMC5714578/ /pubmed/24036877 http://dx.doi.org/10.1120/jacmp.v14i5.4388 Text en © 2013 The Authors. This is an open access article under the terms of the Creative Commons Attribution (http://creativecommons.org/licenses/by/3.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Radiation Oncology Physics
Lučić, Felipe
Sánchez‐Nieto, Beatriz
Caprile, Paola
Zelada, Gabriel
Goset, Karen
Dosimetric characterization and optimization of a customized Stanford Total Skin Electron Irradiation (TSEI) technique
title Dosimetric characterization and optimization of a customized Stanford Total Skin Electron Irradiation (TSEI) technique
title_full Dosimetric characterization and optimization of a customized Stanford Total Skin Electron Irradiation (TSEI) technique
title_fullStr Dosimetric characterization and optimization of a customized Stanford Total Skin Electron Irradiation (TSEI) technique
title_full_unstemmed Dosimetric characterization and optimization of a customized Stanford Total Skin Electron Irradiation (TSEI) technique
title_short Dosimetric characterization and optimization of a customized Stanford Total Skin Electron Irradiation (TSEI) technique
title_sort dosimetric characterization and optimization of a customized stanford total skin electron irradiation (tsei) technique
topic Radiation Oncology Physics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5714578/
https://www.ncbi.nlm.nih.gov/pubmed/24036877
http://dx.doi.org/10.1120/jacmp.v14i5.4388
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