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Dosimetric characterization and optimization of a customized Stanford Total Skin Electron Irradiation (TSEI) technique
Total skin electron irradiation (TSEI) has been used as a treatment for mycosis fungoides. Our center has implemented a modified Stanford technique with six pairs of 6 MeV adjacent electron beams, incident perpendicularly on the patient who remains lying on a translational platform, at 200 cm from t...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5714578/ https://www.ncbi.nlm.nih.gov/pubmed/24036877 http://dx.doi.org/10.1120/jacmp.v14i5.4388 |
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author | Lučić, Felipe Sánchez‐Nieto, Beatriz Caprile, Paola Zelada, Gabriel Goset, Karen |
author_facet | Lučić, Felipe Sánchez‐Nieto, Beatriz Caprile, Paola Zelada, Gabriel Goset, Karen |
author_sort | Lučić, Felipe |
collection | PubMed |
description | Total skin electron irradiation (TSEI) has been used as a treatment for mycosis fungoides. Our center has implemented a modified Stanford technique with six pairs of 6 MeV adjacent electron beams, incident perpendicularly on the patient who remains lying on a translational platform, at 200 cm from the source. The purpose of this study is to perform a dosimetric characterization of this technique and to investigate its optimization in terms of energy characteristics, extension, and uniformity of the treatment field. In order to improve the homogeneity of the distribution, a custom‐made polyester filter of variable thickness and a uniform PMMA degrader plate were used. It was found that the characteristics of a 9 MeV beam with an 8 mm thick degrader were similar to those of the 6 MeV beam without filter, but with an increased surface dose. The combination of the degrader and the polyester filter improved the uniformity of the distribution along the dual field (180 cm long), increasing the dose at the borders of field by 43%. The optimum angles for the pair of beams were [Formula: see text]. This configuration avoided displacement of the patient, and reduced the treatment time and the positioning problems related to the abutting superior and inferior fields. Dose distributions in the transversal plane were measured for the six incidences of the Stanford technique with film dosimetry in an anthropomorphic pelvic phantom. This was performed for the optimized treatment and compared with the previously implemented technique. The comparison showed an increased superficial dose and improved uniformity of the 85% isodose curve coverage for the optimized technique. PACS numbers: 87.53.Bn, 87.55.ne, 87.56.bd |
format | Online Article Text |
id | pubmed-5714578 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-57145782018-04-02 Dosimetric characterization and optimization of a customized Stanford Total Skin Electron Irradiation (TSEI) technique Lučić, Felipe Sánchez‐Nieto, Beatriz Caprile, Paola Zelada, Gabriel Goset, Karen J Appl Clin Med Phys Radiation Oncology Physics Total skin electron irradiation (TSEI) has been used as a treatment for mycosis fungoides. Our center has implemented a modified Stanford technique with six pairs of 6 MeV adjacent electron beams, incident perpendicularly on the patient who remains lying on a translational platform, at 200 cm from the source. The purpose of this study is to perform a dosimetric characterization of this technique and to investigate its optimization in terms of energy characteristics, extension, and uniformity of the treatment field. In order to improve the homogeneity of the distribution, a custom‐made polyester filter of variable thickness and a uniform PMMA degrader plate were used. It was found that the characteristics of a 9 MeV beam with an 8 mm thick degrader were similar to those of the 6 MeV beam without filter, but with an increased surface dose. The combination of the degrader and the polyester filter improved the uniformity of the distribution along the dual field (180 cm long), increasing the dose at the borders of field by 43%. The optimum angles for the pair of beams were [Formula: see text]. This configuration avoided displacement of the patient, and reduced the treatment time and the positioning problems related to the abutting superior and inferior fields. Dose distributions in the transversal plane were measured for the six incidences of the Stanford technique with film dosimetry in an anthropomorphic pelvic phantom. This was performed for the optimized treatment and compared with the previously implemented technique. The comparison showed an increased superficial dose and improved uniformity of the 85% isodose curve coverage for the optimized technique. PACS numbers: 87.53.Bn, 87.55.ne, 87.56.bd John Wiley and Sons Inc. 2013-09-06 /pmc/articles/PMC5714578/ /pubmed/24036877 http://dx.doi.org/10.1120/jacmp.v14i5.4388 Text en © 2013 The Authors. This is an open access article under the terms of the Creative Commons Attribution (http://creativecommons.org/licenses/by/3.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Radiation Oncology Physics Lučić, Felipe Sánchez‐Nieto, Beatriz Caprile, Paola Zelada, Gabriel Goset, Karen Dosimetric characterization and optimization of a customized Stanford Total Skin Electron Irradiation (TSEI) technique |
title | Dosimetric characterization and optimization of a customized Stanford Total Skin Electron Irradiation (TSEI) technique |
title_full | Dosimetric characterization and optimization of a customized Stanford Total Skin Electron Irradiation (TSEI) technique |
title_fullStr | Dosimetric characterization and optimization of a customized Stanford Total Skin Electron Irradiation (TSEI) technique |
title_full_unstemmed | Dosimetric characterization and optimization of a customized Stanford Total Skin Electron Irradiation (TSEI) technique |
title_short | Dosimetric characterization and optimization of a customized Stanford Total Skin Electron Irradiation (TSEI) technique |
title_sort | dosimetric characterization and optimization of a customized stanford total skin electron irradiation (tsei) technique |
topic | Radiation Oncology Physics |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5714578/ https://www.ncbi.nlm.nih.gov/pubmed/24036877 http://dx.doi.org/10.1120/jacmp.v14i5.4388 |
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