Cargando…

A feasibility study using TomoDirect for craniospinal irradiation

The feasibility of delivering craniospinal irradiation (CSI) with TomoDirect is investigated. A method is proposed to generate TomoDirect plans using standard three‐dimensional (3D) beam arrangements on Tomotherapy with junctioning of these fields to minimize hot or cold spots at the cranial/spinal...

Descripción completa

Detalles Bibliográficos
Autores principales: Langner, Ulrich W., Molloy, Janelle A., Gleason, John F., Feddock, Jonathan M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5714580/
https://www.ncbi.nlm.nih.gov/pubmed/24036863
http://dx.doi.org/10.1120/jacmp.v14i5.4304
_version_ 1783283611222409216
author Langner, Ulrich W.
Molloy, Janelle A.
Gleason, John F.
Feddock, Jonathan M.
author_facet Langner, Ulrich W.
Molloy, Janelle A.
Gleason, John F.
Feddock, Jonathan M.
author_sort Langner, Ulrich W.
collection PubMed
description The feasibility of delivering craniospinal irradiation (CSI) with TomoDirect is investigated. A method is proposed to generate TomoDirect plans using standard three‐dimensional (3D) beam arrangements on Tomotherapy with junctioning of these fields to minimize hot or cold spots at the cranial/spinal junction. These plans are evaluated and compared to a helical Tomotherapy and a three‐dimensional conformal therapy (3D CRT) plan delivered on a conventional linear accelerator (linac) for CSI. The comparison shows that a TomoDirect plan with an overlap between the cranial and spinal fields might be preferable over Tomotherapy plans because of decreased low dose to large volumes of normal tissues outside of the planning target volume (PTV). Although the TomoDirect plans were not dosimetrically superior to a 3D CRT linac plan, the patient can be easily treated in the supine position, which is often more comfortable and efficient from an anesthesia standpoint. TomoDirect plans also have only one setup position which obviates the need for matching of fields and feathering of junctions, two issues encountered with conventional 3D CRT plans. TomoDirect plans can be delivered with comparable treatment times to conventional 3D plans and in shorter times than a Tomotherapy plan. In this paper, a method is proposed for creating TomoDirect craniospinal plans, and the dosimetric consequences for choosing different planning parameters are discussed. PACS number: 87.55.D‐
format Online
Article
Text
id pubmed-5714580
institution National Center for Biotechnology Information
language English
publishDate 2013
publisher John Wiley and Sons Inc.
record_format MEDLINE/PubMed
spelling pubmed-57145802018-04-02 A feasibility study using TomoDirect for craniospinal irradiation Langner, Ulrich W. Molloy, Janelle A. Gleason, John F. Feddock, Jonathan M. J Appl Clin Med Phys Radiation Oncology Physics The feasibility of delivering craniospinal irradiation (CSI) with TomoDirect is investigated. A method is proposed to generate TomoDirect plans using standard three‐dimensional (3D) beam arrangements on Tomotherapy with junctioning of these fields to minimize hot or cold spots at the cranial/spinal junction. These plans are evaluated and compared to a helical Tomotherapy and a three‐dimensional conformal therapy (3D CRT) plan delivered on a conventional linear accelerator (linac) for CSI. The comparison shows that a TomoDirect plan with an overlap between the cranial and spinal fields might be preferable over Tomotherapy plans because of decreased low dose to large volumes of normal tissues outside of the planning target volume (PTV). Although the TomoDirect plans were not dosimetrically superior to a 3D CRT linac plan, the patient can be easily treated in the supine position, which is often more comfortable and efficient from an anesthesia standpoint. TomoDirect plans also have only one setup position which obviates the need for matching of fields and feathering of junctions, two issues encountered with conventional 3D CRT plans. TomoDirect plans can be delivered with comparable treatment times to conventional 3D plans and in shorter times than a Tomotherapy plan. In this paper, a method is proposed for creating TomoDirect craniospinal plans, and the dosimetric consequences for choosing different planning parameters are discussed. PACS number: 87.55.D‐ John Wiley and Sons Inc. 2013-09-06 /pmc/articles/PMC5714580/ /pubmed/24036863 http://dx.doi.org/10.1120/jacmp.v14i5.4304 Text en © 2013 The Authors. This is an open access article under the terms of the Creative Commons Attribution (http://creativecommons.org/licenses/by/3.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Radiation Oncology Physics
Langner, Ulrich W.
Molloy, Janelle A.
Gleason, John F.
Feddock, Jonathan M.
A feasibility study using TomoDirect for craniospinal irradiation
title A feasibility study using TomoDirect for craniospinal irradiation
title_full A feasibility study using TomoDirect for craniospinal irradiation
title_fullStr A feasibility study using TomoDirect for craniospinal irradiation
title_full_unstemmed A feasibility study using TomoDirect for craniospinal irradiation
title_short A feasibility study using TomoDirect for craniospinal irradiation
title_sort feasibility study using tomodirect for craniospinal irradiation
topic Radiation Oncology Physics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5714580/
https://www.ncbi.nlm.nih.gov/pubmed/24036863
http://dx.doi.org/10.1120/jacmp.v14i5.4304
work_keys_str_mv AT langnerulrichw afeasibilitystudyusingtomodirectforcraniospinalirradiation
AT molloyjanellea afeasibilitystudyusingtomodirectforcraniospinalirradiation
AT gleasonjohnf afeasibilitystudyusingtomodirectforcraniospinalirradiation
AT feddockjonathanm afeasibilitystudyusingtomodirectforcraniospinalirradiation
AT langnerulrichw feasibilitystudyusingtomodirectforcraniospinalirradiation
AT molloyjanellea feasibilitystudyusingtomodirectforcraniospinalirradiation
AT gleasonjohnf feasibilitystudyusingtomodirectforcraniospinalirradiation
AT feddockjonathanm feasibilitystudyusingtomodirectforcraniospinalirradiation