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Capture of Dense Core Vesicles at Synapses by JNK-Dependent Phosphorylation of Synaptotagmin-4
Delivery of neurotrophins and neuropeptides via long-range trafficking of dense core vesicles (DCVs) from the cell soma to nerve terminals is essential for synapse modulation and circuit function. But the mechanism by which transiting DCVs are captured at specific sites is unknown. Here, we discover...
Autores principales: | Bharat, Vinita, Siebrecht, Michael, Burk, Katja, Ahmed, Saheeb, Reissner, Carsten, Kohansal-Nodehi, Mahdokht, Steubler, Vicky, Zweckstetter, Markus, Ting, Jonathan T., Dean, Camin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5714612/ https://www.ncbi.nlm.nih.gov/pubmed/29166604 http://dx.doi.org/10.1016/j.celrep.2017.10.084 |
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