Laparoscopic complete mesocolic excisions for colonic cancer in the last decade: Five-year survival in a single centre

AIM: To analyse clinical and long-term oncologic results after laparoscopic complete mesocolic excision (CME) for colonic cancer over a 10-year period. METHODS: Consecutive patients who received laparoscopic CME at our hospital from 2007 to 2017 were prospectively registered and retrospectively anal...

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Autores principales: Storli, Kristian Eeg, Lygre, Kristin Bentung, Iversen, Knut Børge, Decap, Maria, Eide, Geir Egil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5714803/
https://www.ncbi.nlm.nih.gov/pubmed/29225732
http://dx.doi.org/10.4240/wjgs.v9.i11.215
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author Storli, Kristian Eeg
Lygre, Kristin Bentung
Iversen, Knut Børge
Decap, Maria
Eide, Geir Egil
author_facet Storli, Kristian Eeg
Lygre, Kristin Bentung
Iversen, Knut Børge
Decap, Maria
Eide, Geir Egil
author_sort Storli, Kristian Eeg
collection PubMed
description AIM: To analyse clinical and long-term oncologic results after laparoscopic complete mesocolic excision (CME) for colonic cancer over a 10-year period. METHODS: Consecutive patients who received laparoscopic CME at our hospital from 2007 to 2017 were prospectively registered and retrospectively analysed. In total, 341 patients were included with tumour-nodal-metastasis (TNM) stages 0-III. RESULTS: The mean age of the patients was 71.9 years. The median length of stay was 5 d. The mean lymph node harvest was 17.8. The mortality rate was 1.2%. Fifteen patients were reoperated on for anastomotic leaks. The local recurrence rate was 2.3%. Five-year TTR and cancer-specific survival CSS were 83.1% and 90.3%. The location of the tumour was not a significant variable for survival in unadjusted and adjusted survival analysis. TNM stage and anastomotic leaks were significant variables with respect to survival. CONCLUSION: Laparoscopic CME results in acceptable complication rates and long-term oncologic results. It is important to avoid anastomotic leaks because of their negative effect on survival.
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spelling pubmed-57148032017-12-08 Laparoscopic complete mesocolic excisions for colonic cancer in the last decade: Five-year survival in a single centre Storli, Kristian Eeg Lygre, Kristin Bentung Iversen, Knut Børge Decap, Maria Eide, Geir Egil World J Gastrointest Surg Clinical Trials Study AIM: To analyse clinical and long-term oncologic results after laparoscopic complete mesocolic excision (CME) for colonic cancer over a 10-year period. METHODS: Consecutive patients who received laparoscopic CME at our hospital from 2007 to 2017 were prospectively registered and retrospectively analysed. In total, 341 patients were included with tumour-nodal-metastasis (TNM) stages 0-III. RESULTS: The mean age of the patients was 71.9 years. The median length of stay was 5 d. The mean lymph node harvest was 17.8. The mortality rate was 1.2%. Fifteen patients were reoperated on for anastomotic leaks. The local recurrence rate was 2.3%. Five-year TTR and cancer-specific survival CSS were 83.1% and 90.3%. The location of the tumour was not a significant variable for survival in unadjusted and adjusted survival analysis. TNM stage and anastomotic leaks were significant variables with respect to survival. CONCLUSION: Laparoscopic CME results in acceptable complication rates and long-term oncologic results. It is important to avoid anastomotic leaks because of their negative effect on survival. Baishideng Publishing Group Inc 2017-11-27 2017-11-27 /pmc/articles/PMC5714803/ /pubmed/29225732 http://dx.doi.org/10.4240/wjgs.v9.i11.215 Text en ©The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved. http://creativecommons.org/licenses/by-nc/4.0/ Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
spellingShingle Clinical Trials Study
Storli, Kristian Eeg
Lygre, Kristin Bentung
Iversen, Knut Børge
Decap, Maria
Eide, Geir Egil
Laparoscopic complete mesocolic excisions for colonic cancer in the last decade: Five-year survival in a single centre
title Laparoscopic complete mesocolic excisions for colonic cancer in the last decade: Five-year survival in a single centre
title_full Laparoscopic complete mesocolic excisions for colonic cancer in the last decade: Five-year survival in a single centre
title_fullStr Laparoscopic complete mesocolic excisions for colonic cancer in the last decade: Five-year survival in a single centre
title_full_unstemmed Laparoscopic complete mesocolic excisions for colonic cancer in the last decade: Five-year survival in a single centre
title_short Laparoscopic complete mesocolic excisions for colonic cancer in the last decade: Five-year survival in a single centre
title_sort laparoscopic complete mesocolic excisions for colonic cancer in the last decade: five-year survival in a single centre
topic Clinical Trials Study
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5714803/
https://www.ncbi.nlm.nih.gov/pubmed/29225732
http://dx.doi.org/10.4240/wjgs.v9.i11.215
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