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Thoracic Aortic Aneurysm Development in Patients with Bicuspid Aortic Valve: What Is the Role of Endothelial Cells?

Bicuspid aortic valve (BAV) is the most common type of congenital cardiac malformation. Patients with a BAV have a predisposition for the development of thoracic aortic aneurysm (TAA). This pathological aortic dilation may result in aortic rupture, which is fatal in most cases. The abnormal aortic m...

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Detalles Bibliográficos
Autores principales: van de Pol, Vera, Kurakula, Kondababu, DeRuiter, Marco C., Goumans, Marie-José
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5714935/
https://www.ncbi.nlm.nih.gov/pubmed/29249976
http://dx.doi.org/10.3389/fphys.2017.00938