ATM and CDK2 control chromatin remodeler CSB to inhibit RIF1 in DSB repair pathway choice

CSB, a member of the SWI2/SNF2 superfamily, is implicated in DNA double-strand break (DSB) repair. However, how it regulates this repair process is poorly understood. Here we uncover that CSB interacts via its newly identified winged helix domain with RIF1, an effector of 53BP1, and that this intera...

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Detalles Bibliográficos
Autores principales: Batenburg, Nicole L., Walker, John R., Noordermeer, Sylvie M., Moatti, Nathalie, Durocher, Daniel, Zhu, Xu-Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5715124/
https://www.ncbi.nlm.nih.gov/pubmed/29203878
http://dx.doi.org/10.1038/s41467-017-02114-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5715124/
https://www.ncbi.nlm.nih.gov/pubmed/29203878
http://dx.doi.org/10.1038/s41467-017-02114-x

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