Albumin/vaccine nanocomplexes that assemble in vivo for combination cancer immunotherapy

Subunit vaccines have been investigated in over 1000 clinical trials of cancer immunotherapy, but have shown limited efficacy. Nanovaccines may improve efficacy but have rarely been clinically translated. By conjugating molecular vaccines with Evans blue (EB) into albumin-binding vaccines (AlbiVax),...

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Detalles Bibliográficos
Autores principales: Zhu, Guizhi, Lynn, Geoffrey M., Jacobson, Orit, Chen, Kai, Liu, Yi, Zhang, Huimin, Ma, Ying, Zhang, Fuwu, Tian, Rui, Ni, Qianqian, Cheng, Siyuan, Wang, Zhantong, Lu, Nan, Yung, Bryant C., Wang, Zhe, Lang, Lixin, Fu, Xiao, Jin, Albert, Weiss, Ido D., Vishwasrao, Harshad, Niu, Gang, Shroff, Hari, Klinman, Dennis M., Seder, Robert A., Chen, Xiaoyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5715147/
https://www.ncbi.nlm.nih.gov/pubmed/29203865
http://dx.doi.org/10.1038/s41467-017-02191-y

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