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Structural enzymology comparisons of multifunctional enzyme, type‐1 (MFE1): the flexibility of its dehydrogenase part
Multifunctional enzyme, type‐1 (MFE1) is a monomeric enzyme with a 2E‐enoyl‐CoA hydratase and a 3S‐hydroxyacyl‐CoA dehydrogenase (HAD) active site. Enzyme kinetic data of rat peroxisomal MFE1 show that the catalytic efficiencies for converting the short‐chain substrate 2E‐butenoyl‐CoA into acetoacet...
Autores principales: | Kasaragod, Prasad, Midekessa, Getnet B., Sridhar, Shruthi, Schmitz, Werner, Kiema, Tiila‐Riikka, Hiltunen, Jukka K., Wierenga, Rik K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5715344/ https://www.ncbi.nlm.nih.gov/pubmed/29226071 http://dx.doi.org/10.1002/2211-5463.12337 |
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