Multiple large osteolytic lesions in a patient with systemic mastocytosis: a challenging diagnosis

Patients with advanced variants of Systemic Mastocytosis may develop destructive bone lesions when massive mast cell (MC) infiltrates are present. Finding of large osteolyses in indolent systemic mastocytosis, typically characterized by low MC burden, should prompt investigations for an alternative...

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Detalles Bibliográficos
Autores principales: Bonifacio, Massimiliano, Zanotti, Roberta, Guardalben, Emanuele, Mimiola, Elda, Scognamiglio, Francesca, Perbellini, Omar, De Matteis, Giovanna, Escribano, Luis, Bonadonna, Patrizia, Grigolato, Daniela, Bissoli, Sergio, Parisi, Alice, Zamò, Alberto, Ambrosetti, Achille, Rossini, Maurizio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Case Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5715414/
https://www.ncbi.nlm.nih.gov/pubmed/29225841
http://dx.doi.org/10.1002/ccr3.1232
Descripción
Sumario:Patients with advanced variants of Systemic Mastocytosis may develop destructive bone lesions when massive mast cell (MC) infiltrates are present. Finding of large osteolyses in indolent systemic mastocytosis, typically characterized by low MC burden, should prompt investigations for an alternative explanation.

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