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Genistein induces apoptosis of colon cancer cells by reversal of epithelial-to-mesenchymal via a Notch1/NF-κB/slug/E-cadherin pathway

BACKGROUND: Genistein has been known to inhibit proliferation and induce apoptosis in several kinds of cancer cells. While knowledge of genistein in regulating epithelial mesenchymal transition (EMT) of colon cancer cells is unknown. METHODS: To investigate the effects and mechanisms of genistein on...

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Detalles Bibliográficos
Autores principales:	Zhou, Panpan, Wang, Chunling, Hu, Zebin, Chen, Wenruo, Qi, Wentao, Li, Aike
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5715491/ https://www.ncbi.nlm.nih.gov/pubmed/29202800 http://dx.doi.org/10.1186/s12885-017-3829-9

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