Activation of G protein‐coupled oestrogen receptor 1 at the onset of reperfusion protects the myocardium against ischemia/reperfusion injury by reducing mitochondrial dysfunction and mitophagy

BACKGROUND AND PURPOSE: Recent evidence indicates that GPER (G protein‐coupled oestrogen receptor 1) mediates acute pre‐ischaemic oestrogen‐induced protection of the myocardium from ischaemia/reperfusion injury via a signalling cascade that includes PKC translocation, ERK1/2/ GSK‐3β phosphorylation...

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Detalles Bibliográficos
Autores principales: Feng, Yansheng, Madungwe, Ngonidzashe B, da Cruz Junho, Carolina Victoria, Bopassa, Jean C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Research Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5715577/
https://www.ncbi.nlm.nih.gov/pubmed/28906548
http://dx.doi.org/10.1111/bph.14033

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