Brain biopsy in the diagnosis of leptomeningeal involvement in stage I chronic lymphocytic leukemia

Leptomeningeal involvement of CLL is usually underdiagnosed as neurological symptoms are unspecific. It is important to carefully evaluate neurological status in these patients and consider this entity between the differential diagnosis of a neurological deterioration as adequate treatment improves...

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Autores principales: Cervilla Muñoz, Eva, Demelo Rodríguez, Pablo, García García, Alejandra, Menarguez Palanca, Javier, del Toro Cervera, Jorge
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Case Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5715602/
https://www.ncbi.nlm.nih.gov/pubmed/29225825
http://dx.doi.org/10.1002/ccr3.1106
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author Cervilla Muñoz, Eva
Demelo Rodríguez, Pablo
García García, Alejandra
Menarguez Palanca, Javier
del Toro Cervera, Jorge
author_facet Cervilla Muñoz, Eva
Demelo Rodríguez, Pablo
García García, Alejandra
Menarguez Palanca, Javier
del Toro Cervera, Jorge
author_sort Cervilla Muñoz, Eva
collection PubMed
description Leptomeningeal involvement of CLL is usually underdiagnosed as neurological symptoms are unspecific. It is important to carefully evaluate neurological status in these patients and consider this entity between the differential diagnosis of a neurological deterioration as adequate treatment improves the prognosis. Imaging techniques, analyses of cerebrospinal fluid, and brain biopsy are useful to establish a definitive diagnosis.
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spelling pubmed-57156022017-12-08 Brain biopsy in the diagnosis of leptomeningeal involvement in stage I chronic lymphocytic leukemia Cervilla Muñoz, Eva Demelo Rodríguez, Pablo García García, Alejandra Menarguez Palanca, Javier del Toro Cervera, Jorge Clin Case Rep Case Reports Leptomeningeal involvement of CLL is usually underdiagnosed as neurological symptoms are unspecific. It is important to carefully evaluate neurological status in these patients and consider this entity between the differential diagnosis of a neurological deterioration as adequate treatment improves the prognosis. Imaging techniques, analyses of cerebrospinal fluid, and brain biopsy are useful to establish a definitive diagnosis. John Wiley and Sons Inc. 2017-10-06 /pmc/articles/PMC5715602/ /pubmed/29225825 http://dx.doi.org/10.1002/ccr3.1106 Text en © 2017 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd. This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial‐NoDerivs (http://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Case Reports
Cervilla Muñoz, Eva
Demelo Rodríguez, Pablo
García García, Alejandra
Menarguez Palanca, Javier
del Toro Cervera, Jorge
Brain biopsy in the diagnosis of leptomeningeal involvement in stage I chronic lymphocytic leukemia
title Brain biopsy in the diagnosis of leptomeningeal involvement in stage I chronic lymphocytic leukemia
title_full Brain biopsy in the diagnosis of leptomeningeal involvement in stage I chronic lymphocytic leukemia
title_fullStr Brain biopsy in the diagnosis of leptomeningeal involvement in stage I chronic lymphocytic leukemia
title_full_unstemmed Brain biopsy in the diagnosis of leptomeningeal involvement in stage I chronic lymphocytic leukemia
title_short Brain biopsy in the diagnosis of leptomeningeal involvement in stage I chronic lymphocytic leukemia
title_sort brain biopsy in the diagnosis of leptomeningeal involvement in stage i chronic lymphocytic leukemia
topic Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5715602/
https://www.ncbi.nlm.nih.gov/pubmed/29225825
http://dx.doi.org/10.1002/ccr3.1106
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