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Anti-aggregant tau mutant promotes neurogenesis

BACKGROUND: The microtubule-associated protein Tau plays a role in neurodegeneration as well as neurogenesis. Previous work has shown that the expression of the pro-aggregant mutant Tau repeat domain causes strong aggregation and pronounced neuronal loss in the hippocampus whereas the anti-aggregant...

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Detalles Bibliográficos
Autores principales:	Joseph, Maria, Anglada-Huguet, Marta, Paesler, Katharina, Mandelkow, Eckhard, Mandelkow, Eva-Maria
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5715613/ https://www.ncbi.nlm.nih.gov/pubmed/29202785 http://dx.doi.org/10.1186/s13024-017-0230-8

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