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MTHFR A1298C polymorphisms reduce the risk of congenital heart defects: a meta-analysis from 16 case-control studies

BACKGROUND: Methylenetetrahydrofolate reductase (MTHFR) plays a crucial role in the hyperhomocysteinemia, which is a risk factor related to the occurrence of congenital heart defect (CHD). However, the association between MTHFR polymorphism and CHD has been inconclusive. METHODS: We conducted an upd...

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Detalles Bibliográficos
Autores principales:	Yu, Di, Zhuang, Zhulun, Wen, Zhongyuan, Zang, Xiaodong, Mo, Xuming
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5715640/ https://www.ncbi.nlm.nih.gov/pubmed/29202788 http://dx.doi.org/10.1186/s13052-017-0425-1

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