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T cell receptor sequencing of early-stage breast cancer tumors identifies altered clonal structure of the T cell repertoire
Tumor-infiltrating T cells play an important role in many cancers, and can improve prognosis and yield therapeutic targets. We characterized T cells infiltrating both breast cancer tumors and the surrounding normal breast tissue to identify T cells specific to each, as well as their abundance in per...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
National Academy of Sciences
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5715779/ https://www.ncbi.nlm.nih.gov/pubmed/29138313 http://dx.doi.org/10.1073/pnas.1713863114 |