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Na leak with gating pore properties in hypokalemic periodic paralysis V876E mutant muscle Ca channel
Type 1 hypokalemic periodic paralysis (HypoPP1) is a poorly understood genetic neuromuscular disease characterized by episodic attacks of paralysis associated with low blood K(+). The vast majority of HypoPP1 mutations involve the replacement of an arginine by a neutral residue in one of the S4 segm...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5715907/ https://www.ncbi.nlm.nih.gov/pubmed/29114033 http://dx.doi.org/10.1085/jgp.201711834 |