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Clinical significance of PCDH10 promoter methylation in diffuse large B-cell lymphoma

BACKGROUND: PCDH10, one of the non-clustered protocadherins, is identified as a tumor suppressor gene in many tumors. Recently, promoter methylation of PCDH10 was found in diffuse large B-cell lymphoma (DLBCL) but not in normal lymph nodes, suggesting that its epigenetic aberrance is essential to th...

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Detalles Bibliográficos
Autores principales: Huang, Wenting, Xue, Xuemin, Shan, Ling, Qiu, Tian, Guo, Lei, Ying, Jianming, Lu, Ning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5715993/
https://www.ncbi.nlm.nih.gov/pubmed/29202805
http://dx.doi.org/10.1186/s12885-017-3810-7

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