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A molecular roadmap of the AGM region reveals BMPER as a novel regulator of HSC maturation

In the developing embryo, hematopoietic stem cells (HSCs) emerge from the aorta-gonad-mesonephros (AGM) region, but the molecular regulation of this process is poorly understood. Recently, the progression from E9.5 to E10.5 and polarity along the dorso-ventral axis have been identified as clear dema...

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Detalles Bibliográficos
Autores principales: McGarvey, Alison C., Rybtsov, Stanislav, Souilhol, Céline, Tamagno, Sara, Rice, Ritva, Hills, David, Godwin, Duncan, Rice, David, Tomlinson, Simon R., Medvinsky, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5716029/
https://www.ncbi.nlm.nih.gov/pubmed/29093060
http://dx.doi.org/10.1084/jem.20162012