cGAMP: A tale of two signals

In this issue of JEM, Swanson et al. (https://doi.org/10.1084/jem.20171749) report an unanticipated role for cGAMP in priming and activation of inflammasomes in addition to its well-characterized function as an endogenous second messenger inducing type I interferons in the cytosolic DNA-sensing path...

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Detalles Bibliográficos
Autores principales: Kuriakose, Teneema, Kanneganti, Thirumala-Devi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2017
Materias:
News
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5716046/
https://www.ncbi.nlm.nih.gov/pubmed/29150429
http://dx.doi.org/10.1084/jem.20171925
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author Kuriakose, Teneema
Kanneganti, Thirumala-Devi
author_facet Kuriakose, Teneema
Kanneganti, Thirumala-Devi
author_sort Kuriakose, Teneema
collection PubMed
description In this issue of JEM, Swanson et al. (https://doi.org/10.1084/jem.20171749) report an unanticipated role for cGAMP in priming and activation of inflammasomes in addition to its well-characterized function as an endogenous second messenger inducing type I interferons in the cytosolic DNA-sensing pathway.
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spelling pubmed-57160462018-06-04 cGAMP: A tale of two signals Kuriakose, Teneema Kanneganti, Thirumala-Devi J Exp Med News In this issue of JEM, Swanson et al. (https://doi.org/10.1084/jem.20171749) report an unanticipated role for cGAMP in priming and activation of inflammasomes in addition to its well-characterized function as an endogenous second messenger inducing type I interferons in the cytosolic DNA-sensing pathway. The Rockefeller University Press 2017-12-04 /pmc/articles/PMC5716046/ /pubmed/29150429 http://dx.doi.org/10.1084/jem.20171925 Text en © 2017 Kuriakose and Kanneganti http://www.rupress.org/terms/https://creativecommons.org/licenses/by-nc-sa/4.0/This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms/). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 International license, as described at https://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle News
Kuriakose, Teneema
Kanneganti, Thirumala-Devi
cGAMP: A tale of two signals
title cGAMP: A tale of two signals
title_full cGAMP: A tale of two signals
title_fullStr cGAMP: A tale of two signals
title_full_unstemmed cGAMP: A tale of two signals
title_short cGAMP: A tale of two signals
title_sort cgamp: a tale of two signals
topic News
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5716046/
https://www.ncbi.nlm.nih.gov/pubmed/29150429
http://dx.doi.org/10.1084/jem.20171925
work_keys_str_mv AT kuriakoseteneema cgampataleoftwosignals
AT kannegantithirumaladevi cgampataleoftwosignals

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