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DNA-assisted oligomerization of pore-forming toxin monomers into precisely-controlled protein channels
We have developed a novel approach for creating membrane-spanning protein-based pores. The construction principle is based on using well-defined, circular DNA nanostructures to arrange a precise number of pore-forming protein toxin monomers. We can thereby obtain, for the first time, protein pores w...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5716084/ https://www.ncbi.nlm.nih.gov/pubmed/29088457 http://dx.doi.org/10.1093/nar/gkx990 |