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Aurora Kinase B, a novel regulator of TERF1 binding and telomeric integrity

AURKB (Aurora Kinase B) is a serine/threonine kinase better known for its role at the mitotic kinetochore during chromosome segregation. Here, we demonstrate that AURKB localizes to the telomeres in mouse embryonic stem cells, where it interacts with the essential telomere protein TERF1. Loss of AUR...

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Detalles Bibliográficos
Autores principales:	Chan, Foong Lyn, Vinod, Benjamin, Novy, Karel, Schittenhelm, Ralf B., Huang, Cheng, Udugama, Maheshi, Nunez-Iglesias, Juan, Lin, Jane I., Hii, Linda, Chan, Julie, Pickett, Hilda A., Daly, Roger J., Wong, Lee H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2017
Materias:	Genome Integrity, Repair and Replication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5716096/ https://www.ncbi.nlm.nih.gov/pubmed/29040668 http://dx.doi.org/10.1093/nar/gkx904

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