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Radiochromic film dosimetry of rectal inhomogeneity and applicator attenuation in high dose rate brachytherapy of uterine cervix

Heterogeneities existing in the patient during treatment are neglected, as the treated subject is considered homogeneous in most of the commercially‐available treatment planning systems (TPSs) used for high dose rate (HDR) brachytherapy. The choice of a suitable dosimeter for experimental dosimetry...

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Detalles Bibliográficos
Autores principales: Uniyal, Satish C., Naithani, Umesh C., Sharma, Sunil D., Srivastava, Anoop K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5716133/
https://www.ncbi.nlm.nih.gov/pubmed/22231217
http://dx.doi.org/10.1120/jacmp.v13i1.3654
Descripción
Sumario:Heterogeneities existing in the patient during treatment are neglected, as the treated subject is considered homogeneous in most of the commercially‐available treatment planning systems (TPSs) used for high dose rate (HDR) brachytherapy. The choice of a suitable dosimeter for experimental dosimetry near the HDR source is crucial, mainly due to existence of steep dose gradients. The present work aimed to assess the effect of rectal air heterogeneity and applicator attenuation in the HDR Ir‐192 brachytherapy treatment of carcinoma uterine cervix by utilizing GAFCHROMIC EBT2 film dosimetry. The dose to rectal walls under the condition of rectal air heterogeneity was measured experimentally using EBT2 film in a rectal phantom, and the measurements were validated by the Monte Carlo (MC) simulations. The applicator attenuation was measured by EBT2 film for a commonly used stainless steel uterine tube in a homogeneous water equivalent phantom. The measured doses were compared with the TPS calculated values. In case of the air cavity, the measured dose at the closest rectal surface was 12.8% less than the TPS calculated value due to lack of back scattering, whereas at the farthest rectal surface, it was higher by 24.5% due to no attenuation. The magnitude of attenuation due to the metal applicator was measured as high as 2% when compared with the TPS calculation. The dose reduction at the nearest rectal surface due to the effect of rectal air has indicated a clinically favorable dose distribution within the rectum, whereas the shielding effect posed by the metallic applicator was found to be less significant. Mutual agreement of the measured doses with the MC calculated dose values confirmed the suitability of EBT2 film for clinical dosimetry in HDR brachytherapy. PACS numbers: 87.53.Bn, 87.53.Jw, 87.56.bg, 87.55.Qr