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Dose to craniofacial region through portal imaging of pediatric brain tumors

The purpose of this study was to determine dose to the planning target volume (PTV) and organs at risk (OARs) from portal imaging (PI) of the craniofacial region in pediatric brain tumor patients treated with intensity‐modulated radiation therapy (IMRT). Twenty pediatric brain tumor patients were re...

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Autores principales: Hitchen, Christine J., Osa, Etin‐Osa, Dewyngaert, J. Keith, Chang, Jenghwa, Narayana, Ashwatha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5716140/
https://www.ncbi.nlm.nih.gov/pubmed/22231206
http://dx.doi.org/10.1120/jacmp.v13i1.3385
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author Hitchen, Christine J.
Osa, Etin‐Osa
Dewyngaert, J. Keith
Chang, Jenghwa
Narayana, Ashwatha
author_facet Hitchen, Christine J.
Osa, Etin‐Osa
Dewyngaert, J. Keith
Chang, Jenghwa
Narayana, Ashwatha
author_sort Hitchen, Christine J.
collection PubMed
description The purpose of this study was to determine dose to the planning target volume (PTV) and organs at risk (OARs) from portal imaging (PI) of the craniofacial region in pediatric brain tumor patients treated with intensity‐modulated radiation therapy (IMRT). Twenty pediatric brain tumor patients were retrospectively studied. Each received portal imaging of treatment fields and orthogonal setup fields in the craniofacial region. The number of PI and monitor units used for PI were documented for each patient. Dose distributions and dose‐volume histograms were generated to quantify the maximum, minimum, and mean dose to the PTV, and the mean dose to OARs through PI acquisition. The doses resulting from PI are reported as percentage of prescribed dose. The average maximum, minimum, and mean doses to PTV from PI were [Formula: see text] , [Formula: see text] , and [Formula: see text] , respectively. The mean dose to the OARs from PI were brainstem [Formula: see text] , optic nerves/chiasm [Formula: see text] , cochlea [Formula: see text] , hypothalamus/pituitary [Formula: see text] , temporal lobes [Formula: see text] , thyroid [Formula: see text] , and eyes [Formula: see text]. The mean number of portal images and the mean number of PI monitor units per patient were 58.8 and 173.3, respectively. The dose from PI while treating pediatric brain tumors using IMRT is significant (2%–3% of the prescribed dose). This may result in exceeding the tolerance limit of many critical structures and lead to unwanted late complications and secondary malignancies. Dose contributions from PI should be considered in the final documented dose. Attempts must be made in PI practices to lower the imaging dose when feasible. PACS numbers: 87.55ne, 87.55Qr
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spelling pubmed-57161402018-04-02 Dose to craniofacial region through portal imaging of pediatric brain tumors Hitchen, Christine J. Osa, Etin‐Osa Dewyngaert, J. Keith Chang, Jenghwa Narayana, Ashwatha J Appl Clin Med Phys Radiation Oncology Physics The purpose of this study was to determine dose to the planning target volume (PTV) and organs at risk (OARs) from portal imaging (PI) of the craniofacial region in pediatric brain tumor patients treated with intensity‐modulated radiation therapy (IMRT). Twenty pediatric brain tumor patients were retrospectively studied. Each received portal imaging of treatment fields and orthogonal setup fields in the craniofacial region. The number of PI and monitor units used for PI were documented for each patient. Dose distributions and dose‐volume histograms were generated to quantify the maximum, minimum, and mean dose to the PTV, and the mean dose to OARs through PI acquisition. The doses resulting from PI are reported as percentage of prescribed dose. The average maximum, minimum, and mean doses to PTV from PI were [Formula: see text] , [Formula: see text] , and [Formula: see text] , respectively. The mean dose to the OARs from PI were brainstem [Formula: see text] , optic nerves/chiasm [Formula: see text] , cochlea [Formula: see text] , hypothalamus/pituitary [Formula: see text] , temporal lobes [Formula: see text] , thyroid [Formula: see text] , and eyes [Formula: see text]. The mean number of portal images and the mean number of PI monitor units per patient were 58.8 and 173.3, respectively. The dose from PI while treating pediatric brain tumors using IMRT is significant (2%–3% of the prescribed dose). This may result in exceeding the tolerance limit of many critical structures and lead to unwanted late complications and secondary malignancies. Dose contributions from PI should be considered in the final documented dose. Attempts must be made in PI practices to lower the imaging dose when feasible. PACS numbers: 87.55ne, 87.55Qr John Wiley and Sons Inc. 2012-01-05 /pmc/articles/PMC5716140/ /pubmed/22231206 http://dx.doi.org/10.1120/jacmp.v13i1.3385 Text en © 2012 The Authors. This is an open access article under the terms of the Creative Commons Attribution (http://creativecommons.org/licenses/by/3.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Radiation Oncology Physics
Hitchen, Christine J.
Osa, Etin‐Osa
Dewyngaert, J. Keith
Chang, Jenghwa
Narayana, Ashwatha
Dose to craniofacial region through portal imaging of pediatric brain tumors
title Dose to craniofacial region through portal imaging of pediatric brain tumors
title_full Dose to craniofacial region through portal imaging of pediatric brain tumors
title_fullStr Dose to craniofacial region through portal imaging of pediatric brain tumors
title_full_unstemmed Dose to craniofacial region through portal imaging of pediatric brain tumors
title_short Dose to craniofacial region through portal imaging of pediatric brain tumors
title_sort dose to craniofacial region through portal imaging of pediatric brain tumors
topic Radiation Oncology Physics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5716140/
https://www.ncbi.nlm.nih.gov/pubmed/22231206
http://dx.doi.org/10.1120/jacmp.v13i1.3385
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