Cargando…
The MRPP1/MRPP2 complex is a tRNA-maturation platform in human mitochondria
Mitochondrial polycistronic transcripts are extensively processed to give rise to functional mRNAs, rRNAs and tRNAs; starting with the release of tRNA elements through 5′-processing by RNase P (MRPP1/2/3-complex) and 3′-processing by RNase Z (ELAC2). Here, we show using in vitro experiments that MRP...
Autores principales: | Reinhard, Linda, Sridhara, Sagar, Hällberg, B. Martin |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5716156/ https://www.ncbi.nlm.nih.gov/pubmed/29040705 http://dx.doi.org/10.1093/nar/gkx902 |
Ejemplares similares
-
Human TRUB1 is a highly conserved pseudouridine synthase responsible for the formation of Ψ55 in mitochondrial tRNA(Asn), tRNA(Gln), tRNA(Glu) and tRNA(Pro)
por: Jia, Zidong, et al.
Publicado: (2022) -
The RNA chaperone La promotes pre-tRNA maturation via indiscriminate binding of both native and misfolded targets
por: Vakiloroayaei, Ana, et al.
Publicado: (2017) -
Kti12, a PSTK-like tRNA dependent ATPase essential for tRNA modification by Elongator
por: Krutyhołowa, Rościsław, et al.
Publicado: (2019) -
Regulation of La/SSB-dependent viral gene expression by pre-tRNA 3′ trailer-derived tRNA fragments
por: Cho, Hee, et al.
Publicado: (2019) -
Dynamics of intracellular stress-induced tRNA trafficking
por: Dhakal, Rabin, et al.
Publicado: (2019)