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Striking a balance: regulation of transposable elements by Zfp281 and Mll2 in mouse embryonic stem cells
Transposable elements (TEs) compose about 40% of the murine genome. Retrotransposition of active TEs such as LINE-1 (L1) tremendously impacts genetic diversification and genome stability. Therefore, transcription and transposition activities of retrotransposons are tightly controlled. Here, we show...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5716208/ https://www.ncbi.nlm.nih.gov/pubmed/29036642 http://dx.doi.org/10.1093/nar/gkx841 |