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Heterologous expression, purification and function of the extracellular domain of human RANK

BACKGROUND: Receptor activator of NF-κB ligand (RANKL)/RANK signaling essentially functions within the skeletal system, particularly participating in osteoclastogenesis and bone resorption. In addition, this signaling pathway has also been shown to influence tumor progression as well as the developm...

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Detalles Bibliográficos
Autores principales: Wei, Yilei, Zhan, Yu, Chen, Pengfei, Liu, Zhi, Zhang, Haohao, Liu, Dandan, Zhang, Jie, Yu, Min, Mo, Wei, Zhang, Jun, Zhang, Xiaoren
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5716252/
https://www.ncbi.nlm.nih.gov/pubmed/29202831
http://dx.doi.org/10.1186/s12896-017-0405-y