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Chromosome biorientation and APC activity remain uncoupled in oocytes with reduced volume
The spindle assembly checkpoint (SAC) prevents chromosome missegregation by coupling anaphase onset with correct chromosome attachment and tension to microtubules. It does this by generating a diffusible signal from free kinetochores into the cytoplasm, inhibiting the anaphase-promoting complex (APC...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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The Rockefeller University Press
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5716262/ https://www.ncbi.nlm.nih.gov/pubmed/28978643 http://dx.doi.org/10.1083/jcb.201606134 |