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Selective aggregation of the splicing factor Hsh155 suppresses splicing upon genotoxic stress

Upon genotoxic stress, dynamic relocalization events control DNA repair as well as alterations of the transcriptome and proteome, enabling stress recovery. How these events may influence one another is only partly known. Beginning with a cytological screen of genome stability proteins, we find that...

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Detalles Bibliográficos
Autores principales: Mathew, Veena, Tam, Annie S., Milbury, Karissa L., Hofmann, Analise K., Hughes, Christopher S., Morin, Gregg B., Loewen, Christopher J.R., Stirling, Peter C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5716266/
https://www.ncbi.nlm.nih.gov/pubmed/28978642
http://dx.doi.org/10.1083/jcb.201612018