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A Ragulator–BORC interaction controls lysosome positioning in response to amino acid availability

Lysosomes play key roles in the cellular response to amino acid availability. Depletion of amino acids from the medium turns off a signaling pathway involving the Ragulator complex and the Rag guanosine triphosphatases (GTPases), causing release of the inactive mammalian target of rapamycin complex...

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Detalles Bibliográficos
Autores principales:	Pu, Jing, Keren-Kaplan, Tal, Bonifacino, Juan S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2017
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5716277/ https://www.ncbi.nlm.nih.gov/pubmed/28993468 http://dx.doi.org/10.1083/jcb.201703094

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