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UNC-45a promotes myosin folding and stress fiber assembly

Contractile actomyosin bundles, stress fibers, are crucial for adhesion, morphogenesis, and mechanosensing in nonmuscle cells. However, the mechanisms by which nonmuscle myosin II (NM-II) is recruited to those structures and assembled into functional bipolar filaments have remained elusive. We repor...

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Detalles Bibliográficos
Autores principales: Lehtimäki, Jaakko I., Fenix, Aidan M., Kotila, Tommi M., Balistreri, Giuseppe, Paavolainen, Lassi, Varjosalo, Markku, Burnette, Dylan T., Lappalainen, Pekka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5716280/
https://www.ncbi.nlm.nih.gov/pubmed/29055011
http://dx.doi.org/10.1083/jcb.201703107