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UNC-45a promotes myosin folding and stress fiber assembly
Contractile actomyosin bundles, stress fibers, are crucial for adhesion, morphogenesis, and mechanosensing in nonmuscle cells. However, the mechanisms by which nonmuscle myosin II (NM-II) is recruited to those structures and assembled into functional bipolar filaments have remained elusive. We repor...
Autores principales: | Lehtimäki, Jaakko I., Fenix, Aidan M., Kotila, Tommi M., Balistreri, Giuseppe, Paavolainen, Lassi, Varjosalo, Markku, Burnette, Dylan T., Lappalainen, Pekka |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5716280/ https://www.ncbi.nlm.nih.gov/pubmed/29055011 http://dx.doi.org/10.1083/jcb.201703107 |
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