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Ectopic expression of Pax4 in pancreatic δ cells results in β-like cell neogenesis
The recent demonstration that pancreatic α cells can be continuously regenerated and converted into β-like cells upon ectopic expression of Pax4 opened new avenues of research in the endocrine cell differentiation and diabetes fields. To determine whether such plasticity was also shared by δ cells,...
Autores principales: | Druelle, Noémie, Vieira, Andhira, Shabro, Aidin, Courtney, Monica, Mondin, Magali, Rekima, Samah, Napolitano, Tiziana, Silvano, Serena, Navarro-Sanz, Sergi, Hadzic, Biljana, Avolio, Fabio, Rassoulzadegan, Minoo, Schmid, Herbert A., Mansouri, Ahmed, Collombat, Patrick |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5716283/ https://www.ncbi.nlm.nih.gov/pubmed/29025873 http://dx.doi.org/10.1083/jcb.201704044 |
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