Ragulator—a multifaceted regulator of lysosomal signaling and trafficking

The lysosomal Ragulator complex regulates cell metabolism and growth by coordinating the activities of metabolic signaling pathways with nutrient availability. In this issue, Filipek et al. (2017. J. Cell Biol. https://doi.org/10.1083/jcb.201703061) and Pu et al. (2017. J. Cell Biol. https://doi.org...

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Detalles Bibliográficos
Autores principales: Colaço, Alexandria, Jäättelä, Marja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2017
Materias:
Commentary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5716293/
https://www.ncbi.nlm.nih.gov/pubmed/29138253
http://dx.doi.org/10.1083/jcb.201710039
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author Colaço, Alexandria
Jäättelä, Marja
author_facet Colaço, Alexandria
Jäättelä, Marja
author_sort Colaço, Alexandria
collection PubMed
description The lysosomal Ragulator complex regulates cell metabolism and growth by coordinating the activities of metabolic signaling pathways with nutrient availability. In this issue, Filipek et al. (2017. J. Cell Biol. https://doi.org/10.1083/jcb.201703061) and Pu et al. (2017. J. Cell Biol. https://doi.org/10.1083/jcb.201703094) introduce a role for Ragulator in growth factor– and nutrient-regulated lysosomal trafficking.
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spelling pubmed-57162932018-06-04 Ragulator—a multifaceted regulator of lysosomal signaling and trafficking Colaço, Alexandria Jäättelä, Marja J Cell Biol Commentary The lysosomal Ragulator complex regulates cell metabolism and growth by coordinating the activities of metabolic signaling pathways with nutrient availability. In this issue, Filipek et al. (2017. J. Cell Biol. https://doi.org/10.1083/jcb.201703061) and Pu et al. (2017. J. Cell Biol. https://doi.org/10.1083/jcb.201703094) introduce a role for Ragulator in growth factor– and nutrient-regulated lysosomal trafficking. The Rockefeller University Press 2017-12-04 /pmc/articles/PMC5716293/ /pubmed/29138253 http://dx.doi.org/10.1083/jcb.201710039 Text en © 2017 Colaço and Jäättelä http://www.rupress.org/terms/https://creativecommons.org/licenses/by-nc-sa/4.0/This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms/). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 International license, as described at https://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Commentary
Colaço, Alexandria
Jäättelä, Marja
Ragulator—a multifaceted regulator of lysosomal signaling and trafficking
title Ragulator—a multifaceted regulator of lysosomal signaling and trafficking
title_full Ragulator—a multifaceted regulator of lysosomal signaling and trafficking
title_fullStr Ragulator—a multifaceted regulator of lysosomal signaling and trafficking
title_full_unstemmed Ragulator—a multifaceted regulator of lysosomal signaling and trafficking
title_short Ragulator—a multifaceted regulator of lysosomal signaling and trafficking
title_sort ragulator—a multifaceted regulator of lysosomal signaling and trafficking
topic Commentary
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5716293/
https://www.ncbi.nlm.nih.gov/pubmed/29138253
http://dx.doi.org/10.1083/jcb.201710039
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