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Independent evaluation of an in‐house brachytherapy treatment planning system using simulation, measurement and calculation methods

Accuracy of treatment planning systems may significantly influence the efficacy of brachytherapy. The purpose of this work is a detailed, varied and independent evaluation of an in‐house brachytherapy treatment planning software called STPS. Operational accuracy of STPS was investigated. Geometric t...

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Autores principales: Shirazi, M. A. Mosleh, Faghihi, R., Siavashpour, Z., Nedaie, H.A., Mehdizadeh, S., Sina, S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5716415/
https://www.ncbi.nlm.nih.gov/pubmed/22402384
http://dx.doi.org/10.1120/jacmp.v13i2.3687
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author Shirazi, M. A. Mosleh
Faghihi, R.
Siavashpour, Z.
Nedaie, H.A.
Mehdizadeh, S.
Sina, S.
author_facet Shirazi, M. A. Mosleh
Faghihi, R.
Siavashpour, Z.
Nedaie, H.A.
Mehdizadeh, S.
Sina, S.
author_sort Shirazi, M. A. Mosleh
collection PubMed
description Accuracy of treatment planning systems may significantly influence the efficacy of brachytherapy. The purpose of this work is a detailed, varied and independent evaluation of an in‐house brachytherapy treatment planning software called STPS. Operational accuracy of STPS was investigated. Geometric tests were performed to validate entry and reconstruction of positional information from scanned orthogonal films. MCNP4C Monte Carlo code and TLDs were used for simulation and experimental measurement, respectively. STPS data were also compared with those from a commercial planning system (Nucletron PLATO). Discrepancy values between MCNP and STPS data and also those of PLATO and STPS at Manchester system dose prescription points (AL and AR) of tandem and ovoid configurations were [Formula: see text] and [Formula: see text] , respectively. Similar results were achieved for other investigated configurations. Observed discrepancies between MCNP and STPS at the dose prescription point and at 1 cm from the tip of the vaginal applicator were 4.5% and 25.6% respectively, while the discrepancy between the STPS and PLATO data at those points was 2.3%. The software showed submillimeter accuracy in its geometrical reconstructions. In terms of calculation accuracy, similar to PLATO, as attenuation of the sources and applicator body is not considered, dose was overestimated at the tip of the applicator, but based on the available criteria, dose accuracy at most points were acceptable. Our results confirm STPS's geometrical and operational reliability, and show that its dose computation accuracy is comparable to an established commercial TPS using the same algorithm. PACS number: 87.53.Jw
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spelling pubmed-57164152018-04-02 Independent evaluation of an in‐house brachytherapy treatment planning system using simulation, measurement and calculation methods Shirazi, M. A. Mosleh Faghihi, R. Siavashpour, Z. Nedaie, H.A. Mehdizadeh, S. Sina, S. J Appl Clin Med Phys Radiation Oncology Physics Accuracy of treatment planning systems may significantly influence the efficacy of brachytherapy. The purpose of this work is a detailed, varied and independent evaluation of an in‐house brachytherapy treatment planning software called STPS. Operational accuracy of STPS was investigated. Geometric tests were performed to validate entry and reconstruction of positional information from scanned orthogonal films. MCNP4C Monte Carlo code and TLDs were used for simulation and experimental measurement, respectively. STPS data were also compared with those from a commercial planning system (Nucletron PLATO). Discrepancy values between MCNP and STPS data and also those of PLATO and STPS at Manchester system dose prescription points (AL and AR) of tandem and ovoid configurations were [Formula: see text] and [Formula: see text] , respectively. Similar results were achieved for other investigated configurations. Observed discrepancies between MCNP and STPS at the dose prescription point and at 1 cm from the tip of the vaginal applicator were 4.5% and 25.6% respectively, while the discrepancy between the STPS and PLATO data at those points was 2.3%. The software showed submillimeter accuracy in its geometrical reconstructions. In terms of calculation accuracy, similar to PLATO, as attenuation of the sources and applicator body is not considered, dose was overestimated at the tip of the applicator, but based on the available criteria, dose accuracy at most points were acceptable. Our results confirm STPS's geometrical and operational reliability, and show that its dose computation accuracy is comparable to an established commercial TPS using the same algorithm. PACS number: 87.53.Jw John Wiley and Sons Inc. 2012-03-08 /pmc/articles/PMC5716415/ /pubmed/22402384 http://dx.doi.org/10.1120/jacmp.v13i2.3687 Text en © 2012 The Authors. This is an open access article under the terms of the Creative Commons Attribution (http://creativecommons.org/licenses/by/3.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Radiation Oncology Physics
Shirazi, M. A. Mosleh
Faghihi, R.
Siavashpour, Z.
Nedaie, H.A.
Mehdizadeh, S.
Sina, S.
Independent evaluation of an in‐house brachytherapy treatment planning system using simulation, measurement and calculation methods
title Independent evaluation of an in‐house brachytherapy treatment planning system using simulation, measurement and calculation methods
title_full Independent evaluation of an in‐house brachytherapy treatment planning system using simulation, measurement and calculation methods
title_fullStr Independent evaluation of an in‐house brachytherapy treatment planning system using simulation, measurement and calculation methods
title_full_unstemmed Independent evaluation of an in‐house brachytherapy treatment planning system using simulation, measurement and calculation methods
title_short Independent evaluation of an in‐house brachytherapy treatment planning system using simulation, measurement and calculation methods
title_sort independent evaluation of an in‐house brachytherapy treatment planning system using simulation, measurement and calculation methods
topic Radiation Oncology Physics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5716415/
https://www.ncbi.nlm.nih.gov/pubmed/22402384
http://dx.doi.org/10.1120/jacmp.v13i2.3687
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