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Astragaloside IV attenuates the H(2)O(2)-induced apoptosis of neuronal cells by inhibiting α-synuclein expression via the p38 MAPK pathway
An oxidative stress insult is one of the principal causes of Parkinson's disease. Astragaloside IV (AS-IV), a constituent extracted from Astragalus membranaceus, has been demonstrated to exert antioxidant effects. However, the mechanisms responsible for the antioxidant properties and neuro-prot...
Autores principales: | Liu, Xiang, Zhang, Jun, Wang, Shibo, Qiu, Jinfu, Yu, Chao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5716437/ https://www.ncbi.nlm.nih.gov/pubmed/29039448 http://dx.doi.org/10.3892/ijmm.2017.3157 |
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