Cargando…

The acute glucose lowering effect of specific GPR120 activation in mice is mainly driven by glucagon-like peptide 1

The mechanism behind the glucose lowering effect occurring after specific activation of GPR120 is not completely understood. In this study, a potent and selective GPR120 agonist was developed and its pharmacological properties were compared with the previously described GPR120 agonist Metabolex-36....

Descripción completa

Detalles Bibliográficos
Autores principales: Sundström, Linda, Myhre, Susanna, Sundqvist, Monika, Ahnmark, Andrea, McCoull, William, Raubo, Piotr, Groombridge, Sam D., Polla, Magnus, Nyström, Ann-Christin, Kristensson, Lisbeth, Någård, Mats, Winzell, Maria Sörhede
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5716539/
https://www.ncbi.nlm.nih.gov/pubmed/29206860
http://dx.doi.org/10.1371/journal.pone.0189060