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The acute glucose lowering effect of specific GPR120 activation in mice is mainly driven by glucagon-like peptide 1
The mechanism behind the glucose lowering effect occurring after specific activation of GPR120 is not completely understood. In this study, a potent and selective GPR120 agonist was developed and its pharmacological properties were compared with the previously described GPR120 agonist Metabolex-36....
Autores principales: | Sundström, Linda, Myhre, Susanna, Sundqvist, Monika, Ahnmark, Andrea, McCoull, William, Raubo, Piotr, Groombridge, Sam D., Polla, Magnus, Nyström, Ann-Christin, Kristensson, Lisbeth, Någård, Mats, Winzell, Maria Sörhede |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5716539/ https://www.ncbi.nlm.nih.gov/pubmed/29206860 http://dx.doi.org/10.1371/journal.pone.0189060 |
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