Cargando…

Loss of polarity alters proliferation and differentiation in low-grade endometrial cancers by disrupting Notch signaling

Cell adhesion and apicobasal polarity together maintain epithelial tissue organization and homeostasis. Loss of adhesion has been described as a prerequisite for the epithelial to mesenchymal transition. However, what role misregulation of apicobasal polarity promotes tumor initiation and/or early p...

Descripción completa

Detalles Bibliográficos
Autores principales: Williams, Erin, Villar-Prados, Alejandro, Bowser, Jessica, Broaddus, Russell, Gladden, Andrew B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5716545/
https://www.ncbi.nlm.nih.gov/pubmed/29206870
http://dx.doi.org/10.1371/journal.pone.0189081

Ejemplares similares