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Loss of polarity alters proliferation and differentiation in low-grade endometrial cancers by disrupting Notch signaling
Cell adhesion and apicobasal polarity together maintain epithelial tissue organization and homeostasis. Loss of adhesion has been described as a prerequisite for the epithelial to mesenchymal transition. However, what role misregulation of apicobasal polarity promotes tumor initiation and/or early p...
Autores principales: | Williams, Erin, Villar-Prados, Alejandro, Bowser, Jessica, Broaddus, Russell, Gladden, Andrew B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5716545/ https://www.ncbi.nlm.nih.gov/pubmed/29206870 http://dx.doi.org/10.1371/journal.pone.0189081 |
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